Protein design: a perspective from simple tractable models
نویسنده
چکیده
Recent progress in computational approaches to protein design builds on advances in statistical mechanical protein folding theory. Here, the number of sequences folding into a given conformation is evaluated and a simple condition for a protein model's designability is outlined.
منابع مشابه
Protein design: A perspective from simple tractable models
We review the recent progress in computational approaches to protein design which builds on advances in statistical-mechanical protein folding theory. In particular, we evaluate the degeneracy of the protein code (i.e. how many sequences fold into a given conformation) and outline a simple condition for ''designability`` in a protein model. From this point of view we discuss several popular pro...
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عنوان ژورنال:
- Folding & design
دوره 3 3 شماره
صفحات -
تاریخ انتشار 1998